Showing posts with label MS. Show all posts
Showing posts with label MS. Show all posts

Little Israel makes a Big Impression


Little Israel makes a Big Impression

Israel’s enemies like to conceal the fact that the Jewish State is one of the smallest of nations - dwarfed by its massive Arab neighbors.  Israel’s tiny geographic size contrasts with the immense benefit it brings to the world. And from recent news articles it is noticeable that many of Israel’s greatest and potential successes started very small indeed.

Israel’s Kadimastem has been having much success with its revolutionary technology that uses microscopic stem cells to protect or repair brain function. Pharmaceutical giant Merck is to work with Kadimastem to conduct screening for new treatments into Multiple Sclerosis and other neuro-degenerative diseases. Another Israeli biotech, BrainStorm, has just built a bioreactor to multiply stem cells for advancing its treatment of ALS.  Still at the cellular level, Israel’s Macrocure is launching on NASDAQ to finance its CureXcell white blood cell therapy to treat hard-to-heal and chronic wounds.



Israel’s Hil Applied Medical has recently been granted a patent in Japan for its focused radiation cancer therapy. Hil’s lasers destroy tumors using a beam of protons – some of the smallest matter in the universe.  The Ebola virus may also be invisible to the naked eye, but it is causing havoc and panic across Africa.  Israeli biotech Protalix has offered its facilities to produce the experimental vaccine ZMapp that has been having some success in treating Ebola victims.  Separately, Israeli doctors are giving Cameroon medics training on how to fight the virus and Israeli biochemists are working hard to develop another vaccine.  Meanwhile Jerusalem-based Argaman Technologies employs high-powered ultrasound to impregnate textiles with accelerated Copper Oxide in order to prevent the spread of bacteria and viruses such as Ebola.

Israel is a small country but certainly punches well above its weight on medical matters.  The exclusive International Society of Orthopedic Centers (ISOC) has expanded its membership to include just one hospital in the Middle East:  Jerusalem’s Hadassah Medical Center.  ISOC members must perform a minimum of 5,000 orthopedic surgeries each year.  Then there is the example of the European Society of Anesthesiology (ESA), which has over 18,000 members in 40 countries.  It has just elected Israel’s Dr Zev Goldik as its new President.

Jewish ethical teachings state that saving the life of one person is like saving an entire world.  Israeli doctors apply this ethos equally to Jews and to non-Jews.  During the past few weeks this included a unique kidney transplant to save a 14-year-old Gaza boy with obstructed blood vessels; operating on a blind 12-year-old Syrian boy brought to Israel on a donkey by his brother; delivering the baby of a Syrian woman fleeing from Quneitra (the seventh Syrian baby born at Ziv medical center in Safed); treating the 366th Syrian civil war casualty brought into Ziv (a 47-year-old Syrian woman who had lost limbs) and heart surgery for a sick Yazidi child from Northern Iraq.  No wonder Israeli Arabs say that Israel is the safest place for an Arab in the Middle East.



Israel is one of the world’s leading countries in the field of nanotechnology – building products and materials at the molecular level.  Scientists at the Hebrew University of Jerusalem are researching colloidal semiconductor nanocrystals - tiny synthetic particles containing metal impurities that don’t exist in nature but could have exciting implications for electronics, solar power and medicine.  On a slightly larger scale, Israel’s OriginGPS has developed the world’s smallest GPS chip.  Named “The Micro Hornet GPS” it is only 10x10x5.8mm and weighs merely 2.5 grams.  It has the capability to be incorporated in clothing, automobiles and any valuable item that requires its location to be tracked.  Staying with microelectronics, Israeli-Arab start-up SolidRun has developed the first scalable computer that is no bigger than a credit card.



Finally, here’s something for all those shortsighted media professionals who find it so difficult to see the huge benefits that Israel brings to the world.  Israeli start-up LOOK has developed a device for finding misplaced spectacles.  A tiny attachment to the spectacles connects wirelessly via an app to any mobile device.


Of course, there is a much simpler way for these people to see tiny Israel more clearly. 

They just need to try opening their eyes.

Michael Ordman writes a free weekly newsletter containing positive news stories about Israel.
For a free subscription, email a request to michael.goodnewsisrael@gmail.com

Seven Weeks (Part 1) - Israeli Medical Treatments



I’ve been absent from the blog scene for around seven weeks due to illness – exactly the same amount of time as between the Jewish festival of Passover and the upcoming festival of Shavuot (Pentecost).  During those seven weeks I just about managed to keep track of the recent accomplishments of the Jewish State.  And Israel’s advances with medical treatments during the past seven weeks have been simply amazing.

My jaw dropped when just last week, in clinical trials, a human patient with deficient jawbone received a successful bone transplant using bone grown in the laboratories of Israel’s Bonus BioGroup. The patient’s own fat cells were the original source tissue, which means almost zero chance of rejection by the body’s immune system.  In the laboratories of Israel’s Technion, scientists have engineered muscle tissue containing major blood vessels for repairing damaged abdomens.  A successful transplant was performed in clinical trials, suggesting that full abdominal surgery in humans using laboratory-generated tissue will soon be possible.


 

Full heart transplants are still very risky, and many Israeli innovations reduce their necessity.  Israel’s V Wave has developed an implant-able shunt – a device that treats congestive heart failure patients by reducing pressure on the muscle controlling the blood flow between the heart chambers.  The first patient to receive the shunt is already experiencing an improved condition.  Meanwhile, researchers at the Hebrew University of Jerusalem have discovered that the protein Erbin can help prevent the irreversible damage to the heart when it attempts to enlarge itself in the final stage before heart failure.

Several Israeli companies produce devices to protect patients during heart operations. One - Keystone Heart - has just raised the required finance to trial its TriGuard filter. TriGuard protects the brain from blood clots and dangerous material (emboli) released during heart valve replacements and other cardiovascular procedures.  Gardia’s WIRON devices, on the other hand, place filters such as the TriGuard into the arteries prior to those procedures. Surgeons at Poland’s John Paul II hospital have recently completed successful trials of the WIRON. 

There were at least three Israeli-led advances in the fight against cancer during the past seven weeks.  Firstly, in the Research & Development labs of EventusDx, on the outskirts of Jerusalem they have developed a blood test to detect breast cancer.  Secondly, the US Food and Drugs Administration has just approved Teva’s Synribo therapy for home use in treating adults with chronic or accelerated phase Chronic Myeloid Leukemia (CML).  Finally, the US FDA has also approved the Duet scanning system, developed by Israeli biotech BioView, for the detection of mutations in lung cancer.
 


There was positive news in the past seven weeks for sufferers of three types of brain diseases.  Tel Aviv University researchers discovered a protein that reverses some of the damage caused by Alzheimer’s.  Ben-Gurion University scientists have developed a treatment using Losartan (marketed as Cozaar) that reduces seizures significantly in epilepsy sufferers.  And multiple sclerosis sufferers who experience fatigue (common with the illness) may soon benefit from the vitamin D analog synthesized by Dr Anat Achiron of Israel’s Sheba Medical Center in Tel-Hashomer.

Two Israeli brain disease treatments are getting more global exposure.  Japan’s Takeda has signed a deal to commercialize Teva’s rasagiline treatment for Parkinson’s, for use in Japan.  And Professor Dimitrios Karussis will this week present the progress of the Jerusalem trials of BrainStorm’s ALS stem cell treatment to the Joint Congress of European Neurology in Istanbul, Turkey.


Seven weeks has seen many breakthroughs in the understanding of the genetic causes of disease.  Scientists at the Hebrew University of Jerusalem (HUJ) have demonstrated the molecular basis of Prader-Willi syndrome (PWS).  Other HUJ geneticists have identified the DNA on/off switch that explains why different species of animals can have so many identical genes.  Tel Aviv University scientists have pinpointed the genetic regulator “switch” that was corrupted by the drug thalidomide and caused so many deaths and deformities in babies 57 years ago.  Scientists at Israel’s Bar Ilan University have identified the gene that controls production of probiotic bacteria in the gut that protects against ulcerative colitis. 

Finally, maybe the research of Weizmann Institute graduate Leemor Joshua-Tor will one day prevent many genetic diseases.  She has discovered a protein that can destroy defective genes in the RNA that are responsible for viruses and diseases such as macular degeneration and cancer.

Just some of the latest incredible medical achievements from the Jewish State.  Be well.

Michael Ordman writes a free weekly newsletter containing positive news stories about Israel.
For a free subscription, email a request to michael.goodnewsisrael@gmail.com